House

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"House," an innovative take on the medical drama, solves mysteries where the villain is a medical malady and the hero is an irreverent, controversial doctor who trusts no one, least of all his patients.

In the past seasons, House has shepherded an elite team of young experts who helped him unravel diagnostic mysteries. In addition, he has a good friend and confidant in oncology specialist Dr. James Wilson (Robert Sean Leonard). There’s some volatile chemistry between House and Dr. Lisa Cuddy (Lisa Edelstein), the Dean of Medicine and hospital administrator; the two are in constant conflict over House’s duties and unconventional behavior, but even she would admit that his brilliance is worth the trouble.